Prefrontal nicotinic receptors control novel social interaction between mice.

@article{Avale2011PrefrontalNR,
  title={Prefrontal nicotinic receptors control novel social interaction between mice.},
  author={Mar{\'i}a Elena Avale and Jonathan Chabout and St{\'e}phanie Pons and Pierre Serreau and F. S. B. Francois de Chaumont and Jean-Christophe Olivo-Marin and Jean-Pierre Bourgeois and Uwe Maskos and Jean-Pierre Changeux and Sylvie Granon},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2011},
  volume={25 7},
  pages={2145-55}
}
Social behavior is a defining mammalian feature that integrates emotional and motivational processes with external rewarding stimuli. It is thus an appropriate readout for complex behaviors, yet its neuronal and molecular bases remain poorly understood. In this study, we investigated the role of the mouse prefrontal area, particularly the involvement of β2-subunit nicotinic receptors (β2*-nAChRs) in a paradigm of social behavior with concurrent motivations. We previously observed that mice… CONTINUE READING
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