Prefrontal modulation of working memory performance in brain injury and disease.

@article{Hillary2006PrefrontalMO,
  title={Prefrontal modulation of working memory performance in brain injury and disease.},
  author={Frank G. Hillary and Helen M. Genova and Nancy D Chiaravalloti and Bart Rypma and John DeLuca},
  journal={Human brain mapping},
  year={2006},
  volume={27 11},
  pages={
          837-47
        }
}
The inter-related cognitive constructs of working memory (WM) and processing speed are fundamental components to general intellectual functioning in humans. Importantly, both WM and processing speed are highly susceptible to disruption in cases of brain injury, neurologic illness, and even in normal aging. A goal of this article is to summarize and critique the functional imaging studies of speeded working memory in neurologically impaired populations. This review focuses specifically on the… CONTINUE READING
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