Prefrontal modulation of visual processing in humans

@article{Barcel2000PrefrontalMO,
  title={Prefrontal modulation of visual processing in humans},
  author={Francisco Barcel{\'o} and Shugo Suwazono and Robert T. Knight},
  journal={Nature Neuroscience},
  year={2000},
  volume={3},
  pages={399-403}
}
Single neuron, evoked potential and metabolic techniques show that attention influences visual processing in extrastriate cortex. We provide anatomical, electrophysiological and behavioral evidence that prefrontal cortex regulates neuronal activity in extrastriate cortex during visual discrimination. Event-related potentials (ERPs) were recorded during a visual detection task in patients with damage in dorsolateral prefrontal cortex. Prefrontal damage reduced neuronal activity in extrastriate… 
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371 Citations
Highly Influential Citations
15
Background Citations
157
Methods Citations
19
Results Citations
24

371 Citations

The Prefrontal Cortex Modulates Category Selectivity in Human Extrastriate Cortex
TLDR
After perturbations to normal PFC function, stimulus-evoked activity in extrastriate cortex exhibited less distinct category selectivity to faces and scenes, highlighting a direct role of PFC in the top–down modulation of bottom–up visual signals.
Task-specific signal transmission from prefrontal cortex in visual selective attention
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The amount of impulse transmission was associated with the level of attentional preparation and the performance of visual selective-attention tasks, consistent with the causal role of prefrontal top-down signals.
Electrophysiological Decoding of Spatial and Color Processing in Human Prefrontal Cortex
Lesions of prefrontal cortex reduce attentional modulation of neuronal responses and synchrony in V4
TLDR
To identify critical sources of attentional feedback to area V4, the entire lateral PFC was removed, including the FEF, in one hemisphere and transected the corpus callosum and anterior commissure in two macaques.
Mechanisms of human attention: event-related potentials and oscillations
Correlates of Auditory Attention and Task Performance in Primary Auditory and Prefrontal Cortex
TLDR
This work extends findings of auditory experience to new behavioral paradigms (utilizing either positive or negative reinforcement) and explores the possible role of top-down signals from prefrontal cortex (PFC) in modulating plasticity in the primary auditory cortex.
Attention to Action: Specific Modulation of Corticocortical Interactions in Humans
TLDR
A supra-modal role for the dorsal prefrontal cortex in attentional selection is suggested, operating within the motor system as well as sensory and mnemonic domains.
Concurrent TMS-fMRI and Psychophysics Reveal Frontal Influences on Human Retinotopic Visual Cortex
Temporal kinetics of prefrontal modulation of the extrastriate cortex during visual attention
TLDR
Electrophysiological evidence of three distinct tonic and phasic PFC inputs to the extrastriate cortex in the initial few hundred milliseconds of stimulus processing provides electrophysical evidence of underlie the pervasive deficits in attention observed in patients with prefrontal lesions.
The Dynamic Nature of Top-Down Signals Originating from Prefrontal Cortex: A Combined fMRI–TMS Study
TLDR
Findings provide evidence for a compensatory mechanism following insults to the brain, and insight into the dynamic nature of top-down signals originating from the PFC.
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