Prefrontal gray matter increases in healthy individuals after lithium treatment: a voxel-based morphometry study.

@article{Monkul2007PrefrontalGM,
  title={Prefrontal gray matter increases in healthy individuals after lithium treatment: a voxel-based morphometry study.},
  author={Emel Serap Monkul and Koji Matsuo and Mark A Nicoletti and Nicole A Dierschke and John P. Hatch and Manish S. Dalwani and Paolo Brambilla and Sheila Cavalcante Caetano and Roberto Sassi and Allan G Mallinger and Jair C. Soares},
  journal={Neuroscience letters},
  year={2007},
  volume={429 1},
  pages={7-11}
}
The objective of this study was to test the hypothesis that 4 weeks of lithium administration would be associated with changes in brain gray and white matter volumes in healthy individuals. Thirteen right-handed healthy volunteers (6 females, mean age=25.9+/-10.0 years) were studied. 3D SPGR MRIs (TR=25 ms, TE=5 ms, slice-thickness=1.5 mm) were acquired using a 1.5 T GE Signa Imaging System, at baseline and after 4 weeks of lithium administration at therapeutically relevant doses. Optimized… CONTINUE READING

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