Prefrontal dopamine efflux during exposure to drug-associated contextual cues in rats with prior repeated methamphetamine.

@article{Lin2007PrefrontalDE,
  title={Prefrontal dopamine efflux during exposure to drug-associated contextual cues in rats with prior repeated methamphetamine.},
  author={Shi-Kwang Lin and Wynn Hwai-Tzong Pan and Pen-Ho Yeh},
  journal={Brain research bulletin},
  year={2007},
  volume={71 4},
  pages={365-71}
}
Conditioned stimulus-reward response and prefrontal dopamine efflux under context previously paired with methamphetamine administration were assessed in rats with or without prior sensitizing regimen. Sensitizing pretreatment was administered with methamphetamine (1mg/kg, every other day for six sessions) for behavioral sensitization. The animals received methamphetamine (1mg/kg) or saline injection (each for six sessions) to pair with distinct contexts on alternate days to induce conditioned… CONTINUE READING

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