Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia

  title={Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia},
  author={Yuan Zhou and Lingzhong Fan and Chenxiang Qiu and Tianzi Jiang},
  journal={Neuroscience Bulletin},
Schizophrenia is hypothesized to arise from disrupted brain connectivity. This “dysconnectivity hypothesis” has generated interest in discovering whether there is anatomical and functional dysconnectivity between the prefrontal cortex (PFC) and other brain regions, and how this dysconnectivity is linked to the impaired cognitive functions and aberrant behaviors of schizophrenia. Critical advances in neuroimaging technologies, including diffusion tensor imaging (DTI) and functional magnetic… CONTINUE READING
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