Prefrontal cortex and schizophrenia. A quantitative magnetic resonance imaging study.

@article{Wible1995PrefrontalCA,
  title={Prefrontal cortex and schizophrenia. A quantitative magnetic resonance imaging study.},
  author={Cynthia G. Wible and Martha Elizabeth Shenton and Hiroto H. Hokama and Ron Kikinis and Ferenc A. Jolesz and David C Metcalf and R. W. McCarley},
  journal={Archives of general psychiatry},
  year={1995},
  volume={52 4},
  pages={279-88}
}
OBJECTIVE To measure prefrontal cortical volume in a group of schizophrenic subjects who presented with mainly positive symptoms and who were previously shown to have volume reductions in left temporal lobe structures. METHOD Fourteen men with chronic schizophrenia and 15 male control subjects were matched for age, IQ, handedness, and parental socioeconomic status. Magnetic resonance images were obtained by means of a 1.5-T magnet, and contiguous 1.5-mm slices of the entire brain were… CONTINUE READING