Prefrontal alterations during memory processing in aging.

  title={Prefrontal alterations during memory processing in aging.},
  author={Lynn T. Nielsen-Bohlman and Robert T. Knight},
  journal={Cerebral cortex},
  volume={5 6},
Studies of human amnesia provide evidence for a short-term memory store with information transfer to long-term memory occurring within 60 sec of encoding. Frontal cortical activation is critical for maintenance of the short-term store, and limbic structure are necessary for access to the long-term store. The P3 and N4 components of the event-related… CONTINUE READING