Preformulation and physicochemical interaction study of furosemide with different solid lipids

@article{Ali2015PreformulationAP,
  title={Preformulation and physicochemical interaction study of furosemide with different solid lipids},
  author={H. Ali and S. Singh and P. Verma},
  journal={Journal of Pharmaceutical Investigation},
  year={2015},
  volume={45},
  pages={385-398}
}
The aim of the present work was to prepare and characterize the matrices of Furosemide (FRSM) with different solid lipids (Compritol 888 ATO, Hydrokote C, Imwitor 491, Imwitor 372P, and Witepsol H12) using Fourier transform infrared (FTIR), Raman, differential scanning calorimetry (DSC), X-ray diffraction (XRD), scanning electron microscopy. The solubility of FRSM in various solid lipids followed the order of; Compritol 888 ATO > Witepsol H12 > Hydrokote C > Imwitor 491 > Imwitor 372. FTIR… Expand

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