Preformed frequencies of cytomegalovirus (CMV)-specific memory T and B cells identify protected CMV-sensitized individuals among seronegative kidney transplant recipients.

@article{Lcia2014PreformedFO,
  title={Preformed frequencies of cytomegalovirus (CMV)-specific memory T and B cells identify protected CMV-sensitized individuals among seronegative kidney transplant recipients.},
  author={Marc L{\'u}cia and Elena Crespo and Edoardo Melilli and Josep Mar{\'i}a Cruzado and Sergi Luque and In{\'e}s Llaud{\'o} and Jordi Niub{\'o} and Juan Torras and Nuria Sab{\'e} Fern{\'a}ndez and Josep Mar{\'i}a Grinyo and Oriol Bestard},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2014},
  volume={59 11},
  pages={1537-45}
}
BACKGROUND Cytomegalovirus (CMV) infection remains a major complication after kidney transplantation. Baseline CMV risk is typically determined by the serological presence of preformed CMV-specific immunoglobulin (Ig) G antibodies, even though T-cell responses to major viral antigens are crucial when controlling viral replication. Some IgG-seronegative patients who receive an IgG-seropositive allograft do not develop CMV infection despite not receiving prophylaxis. We hypothesized that a more… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
17 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…