Preferred codons and amino acid couples in hyperthermophiles

  title={Preferred codons and amino acid couples in hyperthermophiles},
  author={S{\'a}vio Torres de Farias and Maria Christina M. Bonato},
  journal={Genome Biology},
Most organisms grow at temperatures from 20 to 50°C but some prokaryotes, including Archaea and Bacteria, are capable of withstanding higher temperatures, from 60 to >100°C. What makes these cells so resistant to heat? Their biomolecules must be sufficiently stable, especially proteins, to work under these extreme conditions, but the bases for thermostability remains elusive. The preferential usage of certain couples of amino acids and codons in thermal adaptation was investigated, by… CONTINUE READING

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