Preferential translation of cold-shock mRNAs during cold adaptation.

@article{Giuliodori2004PreferentialTO,
  title={Preferential translation of cold-shock mRNAs during cold adaptation.},
  author={Anna Maria Giuliodori and Anna Brandi and Claudio O. Gualerzi and Cynthia L. Pon},
  journal={RNA},
  year={2004},
  volume={10 2},
  pages={265-76}
}
Upon temperature downshift below the lower threshold of balanced growth (approximately 20 degrees C), the Escherichia coli translational apparatus undergoes modifications allowing the selective translation of the transcripts of cold shock-induced genes, while bulk protein synthesis is drastically reduced. Here we were able to reproduce this translational bias in E. coli cell-free extracts prepared at various times during cold adaptation which were found to display different capacities to… CONTINUE READING

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