Preferential metabolism of dihydrotestosterone to androstanediol 17-glucuronide in rat prostate.

Abstract

Androstanediol glucuronide (Adiol G), a marker of peripheral dihydrotestosterone (DHT) metabolism and action, may be conjugated through the hydroxyl group at either the 3-carbon (Adiol 3-G) or 17-carbon (Adiol 17-G) position. Adiol 17-G is the predominant Adiol G isomer derived from DHT in normal men. To determine whether peripheral tissues may be… (More)

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