Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells

@article{Liu1994PreferentialLO,
  title={Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells},
  author={Yanjun Liu and Erik S. Schweitzer and M J Nirenberg and Virginia M Pickel and Cory J. Evans and Robert H Edwards},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={127},
  pages={1419 - 1433}
}
Neurons and endocrine cells have two types of secretory vesicle that undergo regulated exocytosis. Large dense core vesicles (LDCVs) store neural peptides whereas small clear synaptic vesicles store classical neurotransmitters such as acetylcholine, gamma-aminobutyric acid (GABA), glycine, and glutamate. However, monoamines differ from other classical transmitters and have been reported to appear in both LDCVs and smaller vesicles. To localize the transporter that packages monoamines into… CONTINUE READING