Preferential inhibition of oω-conotoxin-sensitive presynaptic Ca2+ channels by adenosine autoreceptors

@article{Yawo1993PreferentialIO,
  title={Preferential inhibition of oω-conotoxin-sensitive presynaptic Ca2+ channels by adenosine autoreceptors},
  author={Hiromu Yawo and Nao Chuhma},
  journal={Nature},
  year={1993},
  volume={365},
  pages={256-258}
}
ADENOSINE is a potent modulator of transmitter release at a variety of synapses. The adenosine Al receptor is assumed to reside in presynaptic terminals and to function as a negative autoreceptor1. How adenosine reduces transmitter release is uncertain2; it may reduce the calcium influx during nerve terminal depolarization by either activating K+ currents3… CONTINUE READING