Preferential increase in high-molecular weight adiponectin after niacin.

  title={Preferential increase in high-molecular weight adiponectin after niacin.},
  author={Sabine Westphal and Claus W Luley},
  volume={198 1},
OBJECTIVE Recently we have demonstrated that treatment with niacin raises adiponectin between 52% and 95% in patients with the metabolic syndrome. In this study we investigated whether all three adiponectin fractions are increased equally, and, secondly, whether the increase in the biologically most active high-molecular weight (HMW) fraction can prevent the deterioration of insulin sensitivity that was also observed after niacin. METHODS AND RESULTS We used sera frozen at -80 degrees C from… CONTINUE READING

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