Preferential incorporation of glucosamine into the galactosamine moieties of chondroitin sulfates in articular cartilage explants.

@article{Noyszewski2001PreferentialIO,
  title={Preferential incorporation of glucosamine into the galactosamine moieties of chondroitin sulfates in articular cartilage explants.},
  author={Elizabeth A. Noyszewski and Kristen Wroblewski and George R. Dodge and Sagar B Kudchodkar and Jennifer Beers and Anupama V Sarma and Raghunath Reddy},
  journal={Arthritis and rheumatism},
  year={2001},
  volume={44 5},
  pages={1089-95}
}
OBJECTIVE To determine the metabolic fate of glucosamine (GlcN) in intact articular cartilage tissue. METHODS Intact articular cartilage explants were cultured for up to 13 days in Dulbecco's modified Eagle's medium supplemented with 1) 1-13C-labeled GlcN, 2) 1-13C-labeled glucose (Glc), or 3) no labeling. Every 3-4 days, samples were removed and frozen… CONTINUE READING
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