Preferential fluorescent staining of heterochromatic regions in human chromosomes 9, 15, and the Y by D 287/170

@article{Schnedl1981PreferentialFS,
  title={Preferential fluorescent staining of heterochromatic regions in human chromosomes 9, 15, and the Y by D 287/170},
  author={Wolfgang Schnedl and R. C. Abraham and Otto Dann and G. Geber and Dieter Schweizer},
  journal={Human Genetics},
  year={1981},
  volume={59},
  pages={10-13}
}
The utility of a newly synthesized chemical variation of DAPI (4′-6-diamidino-2-phenyl-indole), D 287/170, for differential staining of constitutive heterochromatin in man is demonstrated. Direct staining of human chromosomes with D 287/170 results in brilliant fluorescence of the paracentromeric C-band of chromosome 9, of a proximal short-arm segment of chromosome 15 and of certain heterochromatic regions in the Y. Bright, but less conspicuous fluorescence is occassionally seen at the… CONTINUE READING