Preferential expression of truncated isoforms of FOXP1 in primary central nervous system lymphoma.

@article{Courts2009PreferentialEO,
  title={Preferential expression of truncated isoforms of FOXP1 in primary central nervous system lymphoma.},
  author={Cornelius Courts and Anna Brunn and Manuel Montesinos-Rongen and D{\"o}rte Siemer and Volkmar H. J. Hans and Werner Paulus and Otmar Dieter Wiestler and Ralf K{\"u}ppers and Reiner Siebert and Martina Deckert},
  journal={Journal of neuropathology and experimental neurology},
  year={2009},
  volume={68 9},
  pages={
          972-6
        }
}
Forkhead box P1 (FOXP1) protein is a transcription factor involved in cell signaling and regulation of gene expression. The overexpression of FOXP1 in a subgroup of systemic diffuse large B-cell lymphomas has been associated with an exceptionally poor clinical outcome. Data on FOXP1 expression in primary central nervous system lymphomas (PCNSL), that is, diffuse large B-cell lymphomas confined to the central nervous system, are not yet available. We analyzed 43 PCNSL from immunocompetent… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Analysis of proteins

S. Gallagher
  • eds. Current Protocols in Molecular Biology,
  • 2007
VIEW 1 EXCERPT

Malignant lymphomas

M Deckert, W. Paulus
  • Pathology & Genetics of Tumours of the Nervous System
  • 2007
VIEW 1 EXCERPT

Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2005
VIEW 1 EXCERPT