Preferential coupling between dopamine D2 receptors and G-proteins.

  title={Preferential coupling between dopamine D2 receptors and G-proteins.},
  author={Jean Pierre Montmayeur and J Guiramand and Emiliana Borrelli},
  journal={Molecular endocrinology},
  volume={7 2},
The D2 dopamine receptor, an inhibitor of adenylyl cyclase, belongs to the family of seven transmembrane domain G-protein-coupled receptors. This receptor is encoded by two mRNAs produced from the same gene by alternative splicing, here referred to as D2L and D2S. The resultant proteins are identical except for an insertion of 29 amino acids in the putative… CONTINUE READING