Preferential acetazolamide-induced vasodilation based on vessel size and organ: confirmation of peripheral vasodilation with use of colored microspheres.

@article{Taki2001PreferentialAV,
  title={Preferential acetazolamide-induced vasodilation based on vessel size and organ: confirmation of peripheral vasodilation with use of colored microspheres.},
  author={Kentaro Taki and Kazuhisa Oogushi and Kenji Hirahara and Xuefeng Gai and Fumihiro Nagashima and Kazuhiko Tozuka},
  journal={Angiology},
  year={2001},
  volume={52 7},
  pages={483-8}
}
When carbonic anhydrase activity decreases, the regional blood flow (rBF) in organs increases as hypercapnia develops. However, the effects of acetazolamide (AZ)-induced vasodilation have not been estimated with respect to vessel size and organs. The aim of this study was to determine the diameter of the capillaries in various organs that respond to inhibition of carbonic anhydrase activity by AZ. White rabbits were anesthetized with urethane and ketamine and infused with AZ. While the systolic… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Safety of carbonic anhydrase inhibitors.

Expert opinion on drug safety • 2014
View 1 Excerpt

Methazolamide does not impair respiratory work performance in anesthetized rabbits.

American journal of physiology. Regulatory, integrative and comparative physiology • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…