Preexposure to PM2.5 exacerbates acute viral myocarditis associated with Th17 cell.

@article{Xie2013PreexposureTP,
  title={Preexposure to PM2.5 exacerbates acute viral myocarditis associated with Th17 cell.},
  author={Yuquan Xie and Xian Zhang and Zhenyong Tian and Rongfang Jiang and Ruizhen Rachel Chen and Weimin Song and Jinzhuo Zhao},
  journal={International journal of cardiology},
  year={2013},
  volume={168 4},
  pages={3837-45}
}
BACKGROUND It is increasingly recognized that exposure to ambient fine particles (PM(2.5)) is a risk factor for the development of cardiovascular events. This study was to explore the link between PM(2.5) exposure and viral myocarditis in the functional mechanism of Th17 cells. METHODS Male BALB/c mice were administered an intratracheal (i.t.) instillation of 10 mg/kg b.w. PM(2.5) particles. Twenty-four hours later, the mice were injected intraperitoneally (i.p.) with 100 μl of coxsackievirus… CONTINUE READING