Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.

@article{Grant2010PreexposureCF,
  title={Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.},
  author={Robert M. Grant and Javier R. Lama and Peter L Anderson and Vanessa M McMahan and Al Liu and Lorena Vargas and Pedro Goicochea and Martin Casapia and Juan Vicente Guanira-Carranza and Mar{\'i}a E Ram{\'i}rez-Cardich and Orlando Montoya-Herrera and Telmo Fern{\'a}ndez and Valdil{\'e}a Gonçalves Veloso and Susan P. Buchbinder and Suwat Chariyalertsak and Mauro Schechter and Linda-Gail Bekker and Kenneth H. Mayer and Esper Georges Kall{\'a}s and K Rivet Amico and Kathleen Mulligan and Lane R. Bushman and Robert J. Hance and Carmela Ganoza and Patricia A Defechereux and Brian S. Postle and Furong Wang and J. Jeff McConnell and Jia-Hua Zheng and Jean C. Lee and James F. Rooney and Howard S. Jaffe and Ana I. Martinez and David N. Burns and David V. Glidden},
  journal={The New England journal of medicine},
  year={2010},
  volume={363 27},
  pages={
          2587-99
        }
}
BACKGROUND Antiretroviral chemoprophylaxis before exposure is a promising approach for the prevention of human immunodeficiency virus (HIV) acquisition. METHODS We randomly assigned 2499 HIV-seronegative men or transgender women who have sex with men to receive a combination of two oral antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate (FTC-TDF), or placebo once daily. All subjects received HIV testing, risk-reduction counseling, condoms, and management of sexually… 

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