Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway

Abstract

Tuberculosis and helminthic infections coexist in many parts of the world, yet the impact of helminth-elicited Th2 responses on the ability of the host to control Mycobacterium tuberculosis (Mtb) infection has not been fully explored. We show that mice infected with the intestinal helminth Nippostrongylus brasiliensis (Nb) exhibit a transitory impairment of… (More)
DOI: 10.1084/jem.20091473

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@inproceedings{Potian2011PreexistingHI, title={Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway}, author={Julius A. Potian and Wasiulla Rafi and Kamlesh Bhatt and Amanda Moore McBride and William C. Gause and Padmini R. Salgame}, booktitle={The Journal of experimental medicine}, year={2011} }