Preeclampsia: linking placental ischemia with cardiovascular-renal dysfunction.

  title={Preeclampsia: linking placental ischemia with cardiovascular-renal dysfunction.},
  author={Barbara T. Alexander and William A. Bennett and Raouf Ali Khalil and Joey P. Granger},
  journal={News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society},
in the U.S. (6). Despite being one of the leading causes of maternal death and a major contributor to maternal and perinatal morbidity, the mechanisms responsible for the pathogenesis of preeclampsia are unclear. Hypertension associated with preeclampsia develops during pregnancy and remits after delivery, implicating the placenta as a central culprit in the disease. An initiating event in preeclampsia has been postulated to be reduced placental perfusion that leads to widespread dysfunction of… CONTINUE READING


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