Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain.

@article{Hagemeyer2003PredominantlyNE,
  title={Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain.},
  author={Christoph E Hagemeyer and Holger Rosenbrock and Margarethe Ditter and Rolf Knoth and Benedict Volk},
  journal={Neuroscience},
  year={2003},
  volume={117 3},
  pages={521-9}
}
Despite the very small amounts of cytochrome P450 enzymes expressed in different areas and cell populations of the brain as compared with the liver, there is significant evidence for their specific involvement in brain development, function, and plasticity. Nevertheless, the current discussion about occurrence and importance of cerebral cytochrome P450 isoforms is determined by controversial interpretations of their function in general and with respect to single isoforms. Continuing a series of… CONTINUE READING

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