Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor

@inproceedings{Mircheva2009PredominantML,
  title={Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor},
  author={Miryana Mircheva and Diana Boy and Benjamin Weiche and Friederike Hucke and Peter L. Graumann and Hans-Georg Koch},
  booktitle={BMC Biology},
  year={2009}
}
The signal recognition particle (SRP) receptor plays a vital role in co-translational protein targeting, because it connects the soluble SRP-ribosome-nascent chain complex (SRP-RNCs) to the membrane bound Sec translocon. The eukaryotic SRP receptor (SR) is a heterodimeric protein complex, consisting of two unrelated GTPases. The SRβ subunit is an integral membrane protein, which tethers the SRP-interacting SRα subunit permanently to the endoplasmic reticulum membrane. The prokaryotic SR lacks… CONTINUE READING

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