Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration

@article{Hu2015PredominantDR,
  title={Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration},
  author={Zhenzhen Hu and E. Oh and Yeon Bok Chung and J. Hong and K. Oh},
  journal={The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology},
  year={2015},
  volume={19},
  pages={89 - 97}
}
  • Zhenzhen Hu, E. Oh, +2 authors K. Oh
  • Published 2015
  • Chemistry, Medicine
  • The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
  • The aim of this study was to investigate the involvement of dopaminergic receptors (DR) in behavioral sensitization, as measured by locomotor activity, and the over-expression of cocaine- and amphetamine-regulated transcript (CART) peptides after repeated administration of cocaine in mice. Repeated administrations of cocaine induced behavioral sensitization and CART over-expression in mice. The levels of striatal CART mRNA were significantly increased on the 3rd day. CART peptides were over… CONTINUE READING
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