Predominance of serotype-specific mucosal antibody response in Shigella flexneri-infected humans living in an area of endemicity.

@article{RasolofoRazanamparany2001PredominanceOS,
  title={Predominance of serotype-specific mucosal antibody response in Shigella flexneri-infected humans living in an area of endemicity.},
  author={Voahangy Rasolofo-Razanamparany and Anne-Marie Cassel-Beraud and J. Y. Roux and Philippe J Sansonetti and Armelle Phalipon},
  journal={Infection and immunity},
  year={2001},
  volume={69 9},
  pages={5230-4}
}
The mucosal humoral immune response elicited following Shigella flexneri infection in patients living in Antananarivo districts (Madagascar Island) was evaluated by measuring the gut-derived, circulating immunoglobulin A (IgA) antibody-secreting cells (ASC) specific for the major bacterial antigen lipopolysaccharide (LPS). Fifty, 34, 11, and 5% of the S. flexneri-positive patients were infected with serotypes 2a, 1a, 4a, and 3a, respectively. The total number of IgA ASC in infected patients… CONTINUE READING

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