Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation.

@article{Sullivan1988PrednisoneAA,
  title={Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation.},
  author={Keith M. Sullivan and Robert P. Witherspoon and Rainer F Storb and Paul L. Weiden and Nancy Flournoy and Steve Dahlberg and H. Joachim Deeg and Jean E. Sanders and Kristine C Doney and F R Appelbaum},
  journal={Blood},
  year={1988},
  volume={72 2},
  pages={546-54}
}
We conducted a randomized, double-blind comparison of prednisone and placebo (group I) v prednisone and azathioprine (1.5 mg/kg/day) (group II) as early treatment of extensive chronic graft-v-host disease (GVHD). Patients with platelet counts less than 100,000/microL were placed into therapy with prednisone alone (group III). All three groups received identical doses of prednisone (1 mg/kg every other day) and one double-strength trimethoprim-sulfamethoxazole (TMP-SMX) tablet twice daily… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 124 extracted citations

Risk Factors and Outcome of Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation-Results from a Single-Center Observational Study.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2016
View 1 Excerpt

Center for International Blood and Marrow Transplant Research chronic graft-versus-host disease risk score predicts mortality in an independent validation cohort.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2015
View 2 Excerpts

Corticosteroid-Free Primary Treatment of Chronic Extensive Graft-versus-Host Disease Incorporating Rituximab.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2015
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 49 references

Bortin MM (eds): Cellular Immunotherapy of Cancer

plantation, RL in Truitt, RP Gale
Liss, New York, • 1987

Causes of late failure in patients transplanted for acute leukemia

RP Witherspoon, CD Buckner, +4 authors ED Thomas
Bone Marrow Transplant • 1987

Cholesta - sis after azathioprine administration in renal transplant recipients : Report of 7 cases

D Loiseau, F Degos, C Degott, F Carnot, H Kreis
Clin Transplant • 1987

Marrow transplantation for malignant disease.

The American journal of the medical sciences • 1987

ford SW , Thomas ED : Risk factors for airflow obstruction in recipients of bone marrow transplants

Clark iG, DA Schwartz, N Flournoy, KM Sullivan
Ann Intern Med • 1987

Acute and chronic graft-versus-host disease in man

KM Sullivan
Int J Cell Cloning 4:42, • 1986

Similar Papers

Loading similar papers…