Prednisolone or pentoxifylline for alcoholic hepatitis.

@article{Thursz2015PrednisoloneOP,
  title={Prednisolone or pentoxifylline for alcoholic hepatitis.},
  author={Mark R Thursz and Paul G Richardson and Michael Allison and Andrew S. Austin and Megan Bowers and Christopher Paul Day and Nichola Downs and Dermot Gleeson and Alastair J Macgilchrist and Allister Grant and S. J. photographer. Hood and Steven Masson and Anne McCune and Jane Mellor and John G O'grady and David Patch and Ian C. Ratcliffe and Paul Roderick and Louise Stanton and Nikhil Vergis and Mark Wright and Stephen D. Ryder and E H Forrest},
  journal={The New England journal of medicine},
  year={2015},
  volume={372 17},
  pages={
          1619-28
        }
}
BACKGROUND Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver impairment that occurs in patients with a history of heavy and prolonged alcohol use. The short-term mortality among patients with severe disease exceeds 30%. Prednisolone and pentoxifylline are both recommended for the treatment of severe alcoholic hepatitis, but uncertainty about their benefit persists. METHODS We conducted a multicenter, double-blind, randomized trial with a 2-by-2 factorial design to… CONTINUE READING

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