Predisposition locus for major depression at chromosome 12q22-12q23.2.

  title={Predisposition locus for major depression at chromosome 12q22-12q23.2.},
  author={Victor Abkevich and Nicola J. Camp and Charles H. Hensel and Chris D. Neff and Deanna L. Russell and Dana C. Hughes and Agnes M Plenk and Michael R. Lowry and Roberta L Richards and Catherine Alexandra Carter and G Christopher Frech and Steven Stone and Kerry Rowe and Chi Ai Chau and Kathleen Cortado and Angelene Hunt and Karanina Luce and G D O'neil and Jeff Poarch and Jennifer Potter and Gregg H Poulsen and Heidi Saxton and Michelle Bernat-Sestak and Victor Thompson and Alexander Gutin and Mark H. Skolnick and Donna M. Shattuck and Lisa A. Cannon-Albright},
  journal={American journal of human genetics},
  volume={73 6},
Major depression disorder is a common psychiatric disease with a major economic impact on society. In many cases, no effective treatment is available. The etiology of major depression is complex, but it is clear that the disease is, to a large extent, determined genetically, especially among individuals with a familial history of major depression, presumably through the involvement of multiple predisposition genes in addition to an environmental component. As a first step toward identification… CONTINUE READING
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