Predictors of tolerance to chemotherapy in older cancer patients: a prospective pilot study.

@article{Extermann2002PredictorsOT,
  title={Predictors of tolerance to chemotherapy in older cancer patients: a prospective pilot study.},
  author={Martine Extermann and Helen H. W. Chen and Alan B Cantor and Mary Beth Corcoran and Julie M. Meyer and Edward C. Grendys and Denise Cavanaugh and Shirley Antonek and Angela Camarata and William E. Haley and Lodovicco Balducci},
  journal={European journal of cancer},
  year={2002},
  volume={38 11},
  pages={1466-73}
}
Few data are available to help predict which older cancer patient is at risk of developing chemotherapy-related toxicity. This study was a pilot for a project designing a predictive risk score. Chemotherapy patients aged 70 years and older were prospectively enrolled. Chemotherapies were adjusted for their published toxicity. 60 patients were enrolled, 59 were evaluable. Mean dose-intensity was 90.3%, range 33.3-129.0%. 47% of the patients experienced grade 4 haematological and/or grade 3-4 non… CONTINUE READING
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