Predictors of response to proton pump inhibitor therapy among children with significant esophageal eosinophilia.

@article{Dranove2009PredictorsOR,
  title={Predictors of response to proton pump inhibitor therapy among children with significant esophageal eosinophilia.},
  author={Jason E Dranove and Debra S Horn and Miriam A Davis and Kevin M Kernek and Sandeep Kumar Gupta},
  journal={The Journal of pediatrics},
  year={2009},
  volume={154 1},
  pages={96-100}
}
OBJECTIVES To determine predictors of histological response to proton pump inhibitor (PPI) therapy among children with significant esophageal eosinophilia (SEE), defined as >or=15 eosinophils per high powered field (eos/hpf) on esophageal mucosal biopsy (EMB). STUDY DESIGN Response to PPI therapy among children with SEE treated with PPI who underwent repeat EMB was studied retrospectively. Response was defined as <5 eos/hpf on repeat EMB. Characteristics of responders and nonresponders were… CONTINUE READING
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High ntraepithelial eosinophil counts in esophageal squamous epithelium are not specific for osinophilic esophagitis

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