Predictors of response to acute treatment of chronic and double depression with sertraline or imipramine.

@article{Hirschfeld1998PredictorsOR,
  title={Predictors of response to acute treatment of chronic and double depression with sertraline or imipramine.},
  author={Robert M. A. Hirschfeld and James M. Russell and Pedro L. Delgado and Jayne Fawcett and Richard A. Friedman and Wilma M. Harrison and Lorrin Michael Koran and Ivan W Miller and Michael E. Thase and Robert H. Howland and Meghan A. Connolly and Rosalba Miceli},
  journal={The Journal of clinical psychiatry},
  year={1998},
  volume={59 12},
  pages={
          669-75
        }
}
BACKGROUND The literature on predictors of response to treatment of nonchronic major depression has identified shorter duration of illness, acute onset, and less severity of illness as positive predictors. Unfortunately, there are almost no data on predictors of response to treatment for chronic depression. This study examined predictors of response to pharmacotherapy (sertraline or imipramine) in the treatment of outpatients who had DSM-III-R-defined chronic major or double depression… CONTINUE READING

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