Predictors of relapse in major depressive disorder.

  title={Predictors of relapse in major depressive disorder.},
  author={Martin B. Keller and Philip W. Lavori and Catherine E. Lewis and Gerald L. Klerman},
  volume={250 24},
Risk of relapse into an affective episode was high in the months immediately after recovery from a major depressive disorder (MDD) in 141 subjects with nonbipolar depression, without a preexisting dysthymic disorder. The probability of relapse then declined steadily during the duration of the follow-up (median follow-up, 62 weeks from recovery). In patients entering the study during their first affective episode, the Research Diagnostic Criteria secondary subtype of MDD and an older age of… CONTINUE READING