Predictors of recurrence in Sydenham’s chorea: Clinical observation from a single center

  title={Predictors of recurrence in Sydenham’s chorea: Clinical observation from a single center},
  author={Esra Gurkas and Zeynep Selen Karalok and Birce Dilge Taşkın and Ummu Aydogmus and Alev Guven and Aydan Değerliyurt and Omer Bektaş and Cahide Yılmaz},
  journal={Brain and Development},
A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors.
  • A. Orsini, T. Foiadelli, S. Savasta
  • Medicine, Psychology
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
  • 2021
Treatment of Sydenham’s Chorea: A Review of the Current Evidence
It is found that chorea often improves with symptomatic therapy and immunotherapy tends to be reserved for those who fail to respond, and Steroids are beneficial; however, data using IVIG and plasmapheresis are very limited.
Sydenham's Chorea.
Recurrence of Sydenham’s Chorea
  • G. Tata
  • Medicine
    Turkish Journal Of Neurology
  • 2018
A 13-year-old boy was admitted with the complaints of getting fidgety, “wiggling” movements of both hands, dropping objects such as forks, spoons, and pencils from his hands, difficulty in writing, and stumbling feeling of right or left foot while walking, and was diagnosed as having a recurrence of SC and haloperidol treatment was initiated.
Sydenham’s chorea: from pathophysiology to therapeutics
The authors review the pathophysiology, clinical characteristics, and available evidence on therapeutic strategies, the latter including the secondary prevention of GABHS infections, reduction of chorea, and immune modulation.
Sydenham’s chorea: an update on pathophysiology, clinical features and management
This review contemplates the clinical features and pathophysiological aspects of Sydenham’s chorea focusing on their implications for therapeutics and provides an updated perspective on treatment based on antipsychotics, corticosteroids and other immunomodulatory strategies.
Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations
Opinion statementEarly recognition of group A streptococcal pharyngitis and appropriate management with benzathine penicillin using local clinical prediction rules together with validated rapi-strep
Longitudinal outcomes of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS)
The outcomes of this cohort are better than those previously reported for childhood-onset OCD, which may support conceptualization of PANDAS as a subacute illness similar to Sydenham chorea, however, some children developed a chronic course of illness, highlighting the need for research that identifies specific symptoms or biomarkers that can be used to predict the longitudinal course of symptoms in PANDas.
Neurologic complications of rheumatic fever.
Acute Movement Disorders in Childhood
Common and uncommon causes of acute-onset movement disorders are summarized, focusing on clinical presentation and appropriate diagnostic investigations, to provide a useful clinician’s guide to this expanding field of pediatric neurology.


Sydenham's Chorea: A Clinical Follow-Up of 65 Patients
Sydenham's chorea is still an important health problem in Turkey with respect to its morbidity and drug therapy was not needed in 18.5% of the patients.
Recurrence of Sydenham chorea: implications for pathogenesis.
In a significant subgroup of patients, SC recurrence might not be a true relapse of rheumatic fever and might represent either a primary underlying abnormality that renders patients susceptible to developing such a movement disorder or the outcome of permanent subclinical damage to the basal ganglia following the initial SC episode.
Sydenham's chorea--analysis of 27 patients and a review of the literature.
It is concluded that Sydenham's chorea remains a clinical diagnosis and extensive and expensive special investigations are seldom warranted.
Clinical and Neuroimaging Findings of Sydenham’s Chorea
Nonspecific hyperintense white matter abnormalities may be due to the inflammatory process associated with a longer duration of clinical signs and to explain the MRI findings and the pathogenesis of SC, comprehensive studies are needed.
Acute and chronic corticosteroid treatment of ten patients with paralytic form of Sydenham's chorea.
Sydenham's chorea: a new look at an old disease.
  • A. Al-Eissa
  • Medicine
    The British journal of clinical practice
  • 1993
Haloperidol seemed to be an effective and tolerable agent in controlling the motor manifestations of Sydenham's chorea.