Predictors of preclinical Alzheimer disease and dementia: a clinicopathologic study.

@article{Galvin2005PredictorsOP,
  title={Predictors of preclinical Alzheimer disease and dementia: a clinicopathologic study.},
  author={James E. Galvin and Kimberly K Powlishta and Kenneth L Wilkins and D Mckeel and Chengjie Xiong and E. E. Grant and Martha Storandt and John C. Morris},
  journal={Archives of neurology},
  year={2005},
  volume={62 5},
  pages={758-65}
}
BACKGROUND To understand the earliest signs of cognitive decline caused by Alzheimer disease (AD) and other illnesses causing dementia, information is needed from well-characterized individuals without dementia studied longitudinally until autopsy. OBJECTIVE To determine clinical and cognitive features associated with the development of AD or other dementias in older adults. DESIGN Longitudinal study of memory and aging. SETTING Alzheimer's Disease Research Center, St Louis, Mo. MAIN… CONTINUE READING
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