Predictors of non-adherence to methadone maintenance treatment in opioid-dependent individuals: implications for clinicians.

@article{Roux2014PredictorsON,
  title={Predictors of non-adherence to methadone maintenance treatment in opioid-dependent individuals: implications for clinicians.},
  author={Perrine Roux and Caroline Lions and Laurent Michel and Julien G. Cohen and Marion Mora and Fabienne Marcellin and Bruno Spire and Alain Morel and Patrizia Carrieri and Laurent Karila},
  journal={Current pharmaceutical design},
  year={2014},
  volume={20 25},
  pages={
          4097-105
        }
}
BACKGROUND Although methadone maintenance treatment (MMT) is recognized as the treatment of reference for opioid dependence, little information is available regarding the dynamic adherence to methadone and its determinants. With data from the Methaville trial we investigated the evolution of non-adherence to methadone and the effect of pre-treatment and in-treatment factors on longterm non-adherence to methadone. METHODS We selected 145 patients to study adherence to methadone at 3, 6 and 12… CONTINUE READING

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