Predictors of local recurrence after treatment of ductal carcinoma in situ: a meta-analysis.

@article{Boyages1999PredictorsOL,
  title={Predictors of local recurrence after treatment of ductal carcinoma in situ: a meta-analysis.},
  author={John Boyages and Geoff Delaney and R D Jennifer P Taylor},
  journal={Cancer},
  year={1999},
  volume={85 3},
  pages={616-28}
}
BACKGROUND Management of patients with ductal carcinoma in situ (DCIS) is a dilemma, as mastectomy provides nearly a 100% cure rate but at the expense of physical and psychologic morbidity. It would be helpful if we could predict which patients with DCIS are at sufficiently high risk of local recurrence after conservative surgery (CS) alone to warrant postoperative radiotherapy (RT) and which patients are at sufficient risk of local recurrence after CS + RT to warrant mastectomy. The authors… CONTINUE READING

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