Predictors of indeterminate IFN-γ release assay in screening for latent TB in inflammatory bowel diseases.

@article{Papay2011PredictorsOI,
  title={Predictors of indeterminate IFN-γ release assay in screening for latent TB in inflammatory bowel diseases.},
  author={Pavol Papay and Alexander Eser and Stefan Winkler and Sophie Frantal and C Primas and Wolfgang Pf Miehsler and Sieglinde Angelberger and Gottfried Novacek and Andrea Mikulits and Harald Vogelsang and Walter Reinisch},
  journal={European journal of clinical investigation},
  year={2011},
  volume={41 10},
  pages={
          1071-6
        }
}
BACKGROUND IFN-γ release assays (IGRA), widely used for latent tuberculosis screening prior to anti-TNF-α treatment, are limited by indeterminate results in patients under immunomodulatory (IM) therapy. The aim of our observational study was to delineate factors associated with indeterminate IGRA results. METHODS A total of 190 patients with inflammatory bowel disease were included. IGRA was indeterminate if the result of IFN-γ concentration was < 0·35 IU mL(-1) for tuberculosis-specific… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Disease activity is an important factor for indeterminate interferon-γ release assay results in children with inflammatory bowel disease.

  • Journal of pediatric gastroenterology and nutrition
  • 2014
VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED