Predictors of health‐related quality of life and costs in adults with epilepsy: A systematic review

@article{Taylor2011PredictorsOH,
  title={Predictors of health‐related quality of life and costs in adults with epilepsy: A systematic review},
  author={Rod S. Taylor and Josemir W Sander and Rebecca J. Taylor and Gus Baker},
  journal={Epilepsia},
  year={2011},
  volume={52}
}
Purpose:  Given the high burden of epilepsy on both health‐related quality of life (HRQoL) and costs, identification of factors that are predictive of either reduced HRQoL or increased expenditure is central to the better future targeting and optimization of existing and emerging interventions and management strategies for epilepsy. 

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References

SHOWING 1-10 OF 102 REFERENCES

Health‐related quality of life over time since resective epilepsy surgery

Health‐related quality of life (HRQOL) improves after resective epilepsy surgery, but data are limited to short follow‐up in mostly retrospective reports, with minimal consideration of other

The Relative Impact of Anxiety, Depression, and Clinical Seizure Features on Health‐related Quality of Life in Epilepsy

Summary:  Purpose: To determine the independent effects of depression and anxiety on health‐related quality of life (HRQOL) in epilepsy as well as the relative explanatory power of psychiatric

Relationships Between Seizure Severity and Health‐Related Quality of Life in Refractory Localization‐Related Epilepsy

Evaluation of relationships between self‐report measures of seizure severity and health‐related quality of life (HRQOL) in people with refractory localization‐related epilepsy finds no clear relationship between these measures and well-being.

Social Functioning, Psychological Functioning, and Quality of Life in Epilepsy

A series of already existing generic and disease‐specific health status measures were used and considered as determinants of people's QoL, whereasQoL itself was conceived as a general “value judgment” about one's life.

Determinants of quality of life in people with epilepsy.

Relationship Between Seizure Frequency and Costs and Quality of Life of Outpatients with Partial Epilepsy in France, Germany, and the United Kingdom

Summary: Purpose: The relationship between seizure frequency and both health care costs and quality of life (QOL) was investigated in a retrospective, cross‐sectional, multicenter study in France,

Quality of Life of People with Epilepsy: A European Study

The aim of this study was to collect data from as many countries as possible to study the impact of epilepsy and its treatment on people with epilepsy in Europe.

Quality‐of‐Life and Behavioral Outcome Measures in Randomized Controlled Trials of Antiepileptic Drugs: A Systematic Review of Methodology and Reporting Standards

The methodology and use of quality‐of‐life and behavioral measures used in randomized controlled trials (RCTs) of antiepileptic drugs in patients with epilepsy are reviewed.

Epilepsy in Estonia: A Quality‐of‐Life Study

To study the impact of epilepsy and its treatment on people with epilepsy in Estonia and to analyze how it is affected by the characteristics of epilepsy.

Factors affecting the quality of life in patients with epilepsy in Seoul, South Korea

The level of, and factors affecting the quality of life in patients with epilepsy may be different in Korea where social prejudice toward them is still pronounced and these issues have not yet been addressed properly.
...