Predictors of androgen deprivation therapy efficacy combined with prostatic irradiation: the central role of tumor stage and radiation dose.

@article{Williams2011PredictorsOA,
  title={Predictors of androgen deprivation therapy efficacy combined with prostatic irradiation: the central role of tumor stage and radiation dose.},
  author={Scott Garrick Williams and Mark K. Buyyounouski and Larry Llyn Kestin and Gillian Duchesne and Tom Pickles},
  journal={International journal of radiation oncology, biology, physics},
  year={2011},
  volume={79 3},
  pages={724-31}
}
PURPOSE To evaluate the response of clinically localized prostate cancer to various durations of planned androgen deprivation therapy (ADT) and to investigate subgroups predicting response. METHODS AND MATERIALS Data of 3,666 prostate cancer patients treated with either combined ADT and external beam radiotherapy (EBRT) or EBRT alone at four institutions were examined. ADT consisted of neoadjuvant, concurrent, or adjuvant ADT or combinations of these regimens. The primary endpoint was time to… CONTINUE READING

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