Predictors of Long-Term Viral Failure Among Ugandan Children and Adults Treated With Antiretroviral Therapy

@article{Kamya2007PredictorsOL,
  title={Predictors of Long-Term Viral Failure Among Ugandan Children and Adults Treated With Antiretroviral Therapy},
  author={M. Kamya and H. Mayanja-Kizza and A. Kambugu and S. Bakeera-Kitaka and F. Semitala and Patricia Mwebaze-Songa and B. Castelnuovo and Petra Schaefer and L. Spacek and A. Gasasira and E. Katabira and R. Colebunders and T. Quinn and A. Ronald and David L. Thomas and A. Kekitiinwa},
  journal={JAIDS Journal of Acquired Immune Deficiency Syndromes},
  year={2007},
  volume={46},
  pages={187-193}
}
Background:HIV RNA viral load testing is costly and is generally unavailable in resource-limited settings. We identified predictors of viral failure and documented genotypic mutations in a subset of patients with viral failure after 12 months on antiretroviral therapy (ART). Methods:From April 2004 to June 2005, consecutive treatment-naive patients beginning ART at a university clinic in Uganda were enrolled. Clinical information, CD4 cell count, and HIV RNA level were collected at baseline and… Expand
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