Predictors of Delayed Stroke in Patients with Cervical Artery Dissection

@article{Lichy2015PredictorsOD,
  title={Predictors of Delayed Stroke in Patients with Cervical Artery Dissection},
  author={C. Lichy and Antti J. Metso and Alessandro Pezzini and Didier Leys and T M Metso and Philippe Lyrer and St{\'e}phanie Debette and Vincent N. Thijs and Sh{\'e}rine Abboud and Manja Kloss and Yves Samson and Valeria Caso and Maria Sessa and Simone Beretta and Chantal Lamy and Elisabeth de Bustos Medeiros and Anna Bersano and Emmanuel Touz{\'e} and Turgut Tatlisumak and Armin J. Grau and Tobias Brandt and Stefan T Engelter and Caspar Grond-Ginsbach},
  journal={International Journal of Stroke},
  year={2015},
  volume={10},
  pages={360 - 363}
}
Background Stroke in patients with acute cervical artery dissection may be anticipated by initial transient ischemic or nonischemic symptoms. Aim Identifying risk factors for delayed stroke upon cervical artery dissection. Methods Cervical artery dissection patients from the multicenter Cervical Artery Dissection and Ischemic Stroke Patients study were classified as patients without stroke (n = 339), with stroke preceded by nonstroke symptoms (delayed stroke, n = 244), and with stroke at onset… 
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TLDR
DAO independently predicts less favorable functional outcome in patients with CeAD, and further research on vessel patency, collateral status and effects of revascularization therapies particularly in Patients with DAO is warranted.
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TLDR
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TLDR
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TLDR
The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, the study found a high frequency of hypertension, smoking and dyslipidemia.
Computed Tomography Perfusion Can Guide Endovascular Therapy in Bilateral Carotid Artery Dissection
TLDR
A case of traumatic bilateral carotid dissection leading to progressive neurological symptoms and hypoperfusion on computed tomography perfusion (CTP), despite escalation in anticoagulation, which led to emergency carotids stenting.
Cervical and intracranial artery dissections
TLDR
It remains to be shown, whether in CeAD patients presenting with pure local symptoms and without hemodynamic compromise, antiplatelets are sufficient, and whether a dual antiplatelet therapy during the first weeks of treatment is recommendable.
Extracranial Cervical Artery Dissections.
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TLDR
Data suggest that ICAD causing high-grade stenosis and occlusion are more likely to lead to intracranial obstructions and cerebral or retinal ischemic events, and Conversely, ICAD without luminal narrowing cause more local signs and symptoms.
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TLDR
The results are similar to the literature, except for the low frequency of neck pain in ICAD patients and predominance of temporoparietal headache in cervical artery dissection patients.
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TLDR
Men, older patients, and smokers with sVADs may be at increased risk for ischemic events, according to the results of a large retrospective study on 186 patients with first-ever unilateral sVads.
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TLDR
It is suggested that hypertension, although less prevalent than in patients with a non-CEAD IS, could be a risk factor of CEAD, whereas hypercholesterolemia, obesity, and overweightness are inversely associated with CEAD.
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Patients with CAD are a significant link between ischemic stroke and migraine, and this connection may represent a common pathophysiological or genetic background, or both.
Polyarterial clustered recurrence of cervical artery dissection seems to be the rule
TLDR
The recurrence of spontaneous cervical artery dissection (sCAD) involves multiple cervical arteries in sequence more often than previously thought, particularly in patients already receiving antithrombotic therapy.
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TLDR
There were more men than women with spontaneous cervical artery dissection, and men showed a higher frequency of hypertension, migraine, and tinnitus, and outcome and mortality were similar in both sexes.
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TLDR
Nedeltchev et al discuss that they did not detect any beneficial effect of complete recanalization and refer to 2 articles that do not directly support their view; one is a small study on 60 cervical artery dissection patients treated with anticoagulants and the second is a review in Spanish.
CADISP-Genetics: An International Project Searching for Genetic Risk Factors of Cervical Artery Dissections
TLDR
A multinational European network, Cervical Artery Dissection and Ischemic Stroke Patients (CADISP), which aims at increasing the knowledge of the pathophysiological mechanisms of this disease in a large group of patients and will provide detailed and novel data on environmental risk factors and genetic susceptibility to CAD.
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