Predictors, Prevalence, and Outcomes of Early Crystalloid Responsiveness Among Initially Hypotensive Patients With Sepsis and Septic Shock.

@article{Leisman2018PredictorsPA,
  title={Predictors, Prevalence, and Outcomes of Early Crystalloid Responsiveness Among Initially Hypotensive Patients With Sepsis and Septic Shock.},
  author={Daniel E Leisman and Martin E. Doerfler and Sandra M. Schneider and Kevin D Masick and Jason A D'Amore and John K D'Angelo},
  journal={Critical care medicine},
  year={2018},
  volume={46 2},
  pages={189-198}
}
OBJECTIVES The prevalence of responsiveness to initial fluid challenge among hypotensive sepsis patients is unclear. To avoid fluid overload, and unnecessary treatment, it is important to differentiate these phenotypes. We aimed to 1) determine the proportion of hypotensive sepsis patients sustaining favorable hemodynamic response after initial fluid challenge, 2) determine demographic and clinical risk factors that predicted refractory hypotension, and 3) assess the association between… CONTINUE READING
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