Predictive value of vascular endothelial growth factor polymorphisms on the risk of renal cell carcinomas.

@article{Xian2015PredictiveVO,
  title={Predictive value of vascular endothelial growth factor polymorphisms on the risk of renal cell carcinomas.},
  author={W Xian and Hong Zheng and W J Wu},
  journal={Genetics and molecular research : GMR},
  year={2015},
  volume={14 3},
  pages={7634-42}
}
We conducted a case-control study in a Chinese population to assess whether 5 common single-nucleotide polymorphisms in the vascular endothelial growth factor gene (VEGF) affect the risk of renal cell carcinoma (RCC). The study population included 266 RCC patients who were newly diagnosed and histologically confirmed to have RCC as well as 532 cancer-free controls. Genotyping of VEGF -2578C/A, -1156G/A, +1612G/A, +936C/T, and -634G/C was conducted by polymerase chain reaction-restriction… CONTINUE READING