Predictive value of cell cycle markers p53, MDM2, p21, and Ki-67 in superficial bladder tumor recurrence.

@article{Pfister1999PredictiveVO,
  title={Predictive value of cell cycle markers p53, MDM2, p21, and Ki-67 in superficial bladder tumor recurrence.},
  author={Christian Ulrich Pfister and Lynne Moore and Paul Allard and H{\'e}l{\`e}ne Larue and Louis . Compositeur Lacombe and Bernard Tětu and François Meyer and Yves Fradet},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1999},
  volume={5 12},
  pages={
          4079-84
        }
}
The aim of the study was to determine whether the expression of the cell cycle markers p53, MDM2, p21, and Ki-67 was predictive of superficial bladder cancer recurrence and to compare the relative predictive power for tumor recurrence of a cell cycle index based on the number of abnormally expressed cell cycle markers with a clinicopathological index based on primary clinical tumor characteristics. The expression of p53, MDM2, and p21 proteins and the value of the Ki-67 index were analyzed for… CONTINUE READING

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