Predictive value of angiogenic factors and uterine artery Doppler for early- versus late-onset pre-eclampsia and intrauterine growth restriction.

@article{Crispi2008PredictiveVO,
  title={Predictive value of angiogenic factors and uterine artery Doppler for early- versus late-onset pre-eclampsia and intrauterine growth restriction.},
  author={F{\'a}tima Crispi and E Llurba and Carmen Dom{\'i}nguez and Pilar Mart{\'i}n-Gall{\'a}n and Llu{\'i}s Cabero and Eduard Gratac{\'o}s},
  journal={Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology},
  year={2008},
  volume={31 3},
  pages={
          303-9
        }
}
OBJECTIVES To investigate potential differences in the prediction of early- vs. late-onset pre-eclampsia and/or intrauterine growth restriction (PE/IUGR) by second-trimester uterine artery Doppler examination, and measurement of maternal serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFlt1). METHODS Uterine artery mean pulsatility index (PI) and maternal serum PlGF and sFlt1 levels were measured at 24 weeks of gestation in 76 healthy pregnant women and 38 cases… CONTINUE READING

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