Predictive suppression of cortical excitability and its deficit in schizophrenia.

  title={Predictive suppression of cortical excitability and its deficit in schizophrenia.},
  author={Peter Lakatos and Charles E. Schroeder and David I. Leitman and Daniel C. Javitt},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={33 28},
Recent neuroscience advances suggest that when interacting with our environment, along with previous experience, we use contextual cues and regularities to form predictions that guide our perceptions and actions. The goal of such active "predictive sensing" is to selectively enhance the processing and representation of behaviorally relevant information in an efficient manner. Since a hallmark of schizophrenia is impaired information selection, we tested whether this deficiency stems from… CONTINUE READING
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